REDCap

Intervention trials

This searchable database contains the latest intervention studies approved by the LSHTM Research Ethics Committee, along with historical data from the Research Governance and Integrity Office. You can search using keywords and filters to find relevant information, with results sorted in descending order by the review status date of projects. Please note, only projects approved from 2018 onward will appear in your search results. For any questions or assistance, feel free to contact our team at [email protected].

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Returned 383 projects out of 383

MAnagement of Malnutrition in Infants (MAMI) & their mothers: Pilot implementation research towards future scale-up of a Clinical Care Pathway intervention in Senegal & Bangladesh Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Trial of a public health intervention (eg behavioural, education) Senegal,Bangladesh,United Kingdom
A Simplified screen-and-Treat-all prOphylaxis approach in Pregnant women to stop Hepatitis B Virus mother-to-child transmission in Malawi and The Gambia Faculty or Unit of Lead Investigator MRC The Gambia Project type Acceptability/feasibility study Malawi,The Gambia
Development, implementation and evaluation of quality improvement interventions for blood culture services for neonates in a tertiary hospital in Harare, Zimbabwe (CURE Neonates) Faculty or Unit of Lead Investigator Project type Other interventional trial Zimbabwe
Phase-IIIb individually randomized, placebo-controlled trial of on safety of RSVA/B-preF vaccine in pregnant women and efficacy in infants. Faculty or Unit of Lead Investigator MRC The Gambia Project type Other interventional trial Randomised controlled trial The Gambia,Ghana,Kenya,South Africa
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women Faculty or Unit of Lead Investigator MRC Uganda Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase III Uganda
RADIO-TB - Optimal management of radiographically apparent, bacteriologically unconfirmed TB identified through active case finding Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase III Pakistan,Zimbabwe,South Africa,United Kingdom
A Phase 2, Randomized, Open-label, Active Controlled Study to Evaluate the Safety, Tolerability and Immunogenicity of Measles and Rubella Vaccine Microneedle Patches in Healthy Infants, in The Gambia. Faculty or Unit of Lead Investigator MRC The Gambia Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase II The Gambia,United States of America
Evaluating the Effectiveness of Positive Deviance/Hearth, a Non-Specially Formulated Food Approach, to Treat Uncomplicated Moderate Acute Malnutrition in Children 6-59 months of Age in Bangladesh Faculty or Unit of Lead Investigator Project type Other interventional trial Randomised controlled trial Bangladesh
Using Mixed Methods to Investigate the Decline in Vaccine Confidence in Europe Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial United Kingdom,Netherlands,Croatia,Latvia,Slovakia
Evaluating an AI-Based Chatbot to Counter Childhood Vaccine Misinformation in the UK: A Non-Clinical, Online Randomised Controlled Trial Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial United Kingdom
Probiotics in preterm and small for gestational age infants (PROPS) Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Other clinical trial (e.g vitamins) Randomised controlled trial Bangladesh,Ethiopia,Kenya,Nigeria,Pakistan
Implementation research to test acceptability, appropriateness, feasibility, and implementation cost of a digital dashboard to monitor newborn data accuracy: Pilot Project in Ethiopia and Uganda Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Acceptability/feasibility study Ethiopia,Uganda
MARGUERITE: A PHASE 3 STUDY OF REVACCINATION IN SUBSEQUENT PREGNANCIES WITH RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINE AND DURATION OF PROTECTION OF A SINGLE DOSE Faculty or Unit of Lead Investigator MRC The Gambia Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase III The Gambia,South Africa,United States of America,Argentina
Rehabilitation with embedded mental health and diabetes services to address multiple long-term conditions among people with tuberculosis (RESTORE) Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial Zimbabwe
A Phase IIb randomised controlled trial of the safety, immunogenicity and efficacy of the malaria vaccine candidates R78C with Matrix-M™, and the combination of RH5.1 and R21 with Matrix-M™. Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase II United Kingdom,Burkina Faso
A study to evaluate safety, reactogenicity, and immune response of GVGH iNTS-TCV vaccine against invasive nontyphoidal Salmonella disease and Typhoid Fever in infants Faculty or Unit of Lead Investigator MRC The Gambia Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase II The Gambia,Italy
Early Aortic Repair in patients Needing Endovascular/open Surgery for Type B Aortic Dissection (EARNEST): A randomised trial Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Clinical trial of a surgical procedure Randomised controlled trial United Kingdom
REvascularisation for heart failure with PReserved ejection fraction and Ischaemia: EValuation of Efficacy and mechanistic Description (REPRIEVED) Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Other interventional trial Randomised controlled trial United Kingdom
Coordinated Care for Alcohol Problems (CCAP): a Randomised Controlled Trial from Goa, India Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial India
ValgaNciclovIR for CMV Viraemia in AdvaNced HIV diseAse A phase 2b Randomised Placebo Controlled Trial of Valganciclovir for Cytomegalovirus Viraemia in adults and adolescents with Advanced HIV Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase II Uganda,South Africa