REDCap

Intervention trials

This searchable database contains the latest intervention studies approved by the LSHTM Research Ethics Committee, along with historical data from the Research Governance and Integrity Office. You can search using keywords and filters to find relevant information, with results sorted in descending order by the review status date of projects. Please note, only projects approved from 2018 onward will appear in your search results. For any questions or assistance, feel free to contact our team at [email protected].

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Returned 352 projects out of 352

A phase III Randomized Placebo Controlled Study to Assess Efficacy and Safety of Crizanlizumab versus placebo in Adolescent and Adult Sickle Cell Disease Patients with Frequent Vaso-Occlusive Crises Faculty or Unit of Lead Investigator MRC Uganda Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase III Uganda
A Phase 1b, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Mosquitocidal Activity of Single Oral Doses of Lotilaner in Healthy Participants in West Africa Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase I Mali
Little Doctors for reducing the risk of human Nipah virus (NiV) exposure in Bangladesh: A pilot evaluation Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Acceptability/feasibility study Randomised controlled trial Bangladesh
Implementation research to co-design neonatal case notes in health facilities in high mortality settings Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Acceptability/feasibility study Central African Republic,United Republic of Tanzania,United Kingdom
VIEW: Valuing Individuals by Engaging With care - An RCT on Compassion Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial India,United Kingdom
Implementation research of educational activities for newborn and stillbirth routine data in health facilities in high mortality settings Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Acceptability/feasibility study Central African Republic,United Republic of Tanzania,United Kingdom
Lung Ultrasound in Pulmonary Tuberculosis: Evaluating Image Acquisition Protocol and Probe Accuracy in Zambia Faculty or Unit of Lead Investigator Project type Clinical investigation or other study of a medical device (eg blood pressure cuff) Zambia
Adoption and Implementation Strategies to Enhance Fidelity of Oral Azithromycin Routine Use in Preventing Maternal Sepsis amongst Women with Planned Vaginal Delivery in Nigeria Faculty or Unit of Lead Investigator Project type Other interventional trial Randomised controlled trial Nigeria
Determining the optimal approach to delivery of a malaria vaccine in seasonal transmission areas through phase 4 implementation research in Guinea Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Trial of a public health intervention (eg behavioural, education) Guinea
Delivering Effective Non-Invasive Ventilation in Motor Neuron Disease Faculty or Unit of Lead Investigator Public Health and Policy (PHP) Project type Other interventional trial Randomised controlled trial United Kingdom
Determining optimal approach to deliver malaria vaccine in seasonal transmission areas through Phase 4 implementation research in Mali Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Trial of a public health intervention (eg behavioural, education) Mali
Optimisation and pilot RCT of the 'Belonging' brief intervention to build school belonging, promote mental health and prevent violence in secondary schools Faculty or Unit of Lead Investigator Public Health and Policy (PHP) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial United Kingdom
Feasibility of a community-based intervention for the diagnosis and management of hypertension in two rural populations in Kenya and The Gambia Faculty or Unit of Lead Investigator MRC The Gambia Project type Acceptability/feasibility study The Gambia,Kenya,United Kingdom
Protecting mothers and their infants through screening and comprehensive management of sexually transmitted infections in antenatal care in Zimbabwe (PROMISE) Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial Zimbabwe
A Phase 4, Open-Label, Cabotegravir + Rilpivirine Long-Acting Injection Rollover Study Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Clinical trial of an investigational medicinal product (eg drugs) Uganda,Kenya,South Africa
Feasibility and acceptability of a wellbeing app to facilitate more sustainable and healthier diets: a pilot trial Faculty or Unit of Lead Investigator Project type Acceptability/feasibility study Randomised controlled trial United Kingdom
Population-pharmacokinetics, safety and tolerability of sustained-release flucytosine pellets for the treatment of asymptomatic cryptococcal antigen-positive individuals: a single-arm trial Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Clinical trial of an investigational medicinal product (eg drugs) South Africa
The development of Learning Health System protocols for the management of hypertension, type 2 diabetes, and chronic kidney disease in primary care in Chiang Mai and Lamphun, Thailand Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Acceptability/feasibility study Thailand
The effects of tranexamic acid on anaemia, menstrual health and the wellbeing of women: an international randomised, placebo-controlled trial among menstruating women with anaemia Faculty or Unit of Lead Investigator Epidemiology and Population Health (EPH) Project type Clinical trial of an investigational medicinal product (eg drugs) Randomised controlled trial Phase III Nigeria,Pakistan,United Republic of Tanzania,United Kingdom,France
Evaluating the individual and combined effects of hand hygiene promotion and hardware provision on handwashing with soap behaviour in peri-urban Lusaka, Zambia: a factorial randomised-controlled trial Faculty or Unit of Lead Investigator Infectious and Tropical Diseases (ITD) Project type Trial of a public health intervention (eg behavioural, education) Randomised controlled trial Zambia